Anti-PI3K/PIK3R1 抗体说明书

Anti-PI3K/PIK3R1抗体说明书

RabbitAnti-PI3K/PIK3R1抗体说明书
ABCAM
Cat.Number: Rs-0128R 
Quantitysize: 0.1ml （dilutewithpH7.4   0.01MPBSordiluentofantibody）
 
Background: Theenzymephosphatidylinositol3kinase（PI3kinase）isalipidkinasethatgeneratesphosphatidylinositol3,4,5-triphosphateinresponsetoreceptoractivationinmanysignaltransductionpathways.ClassIAPI3Ksexistasaheterodimerofacatalytic110kDa（p110）andaregulatoryp85subunit（e.g.p85alpha）.p85alphaisanadaptormoleculethatregulatestheactivityofthecatalyticp110subunitbybindingtophosphorylatedreceptortyrosinekinases（RTKs）throughitsSH2domainandmediatingtheinteractionbetweenp110andtheplasmamembrane.p85alphaisnecessaryforinsulin-stimulatedincreaseinglucoseuptakeandglycogensynthesisininsulin-sensitivetissues.

RabbitAnti-PI3K/PIK3R1抗体说明书
Specificity:     • Anti-PI3Kisarabbitmonoclonalantibodyunconjugated
 • specificforPI3Kofmouse  
•epitopemappingneartheCterminusofPI3Kofmouse  
• useforwesternblotting,elisa,immunoprecipitation    
  andimmunohistochemistry
• ProteinAaffinitychromatographypurification,purity:>95%
•Isotype:IgG  •molwt:48kDa
Application:    •Westernblotting:1:100-500
•Immunohistochemistry:1:100-500
•ELISA:1:500-1000
• Optimalworkingdilutionsmustbedeterminedbytheenduser.

Storage:  Storeat–20ºCforoneyear.Avoidrepeatedfreeze/thawcycles.Thelyophilizedantibodyisstableatroomtemperatureforatleastonemonthandforgreaterthanayearwhenkeptat-20ºC.WhenreconstitutedinsterilepH7.40.01MPBSordiluentofantibodytheantibodyisstableforatleasttwoweeksat2-4ºC.
 
ImportantNote: Thisproductassuppliedis intendedforresearchuseonly,notforuseinhuman,therapeuticordiagnosticapplications.

RabbitAnti-PI3K/PIK3R1抗体说明书
 

  
2004-07-13