CYP2D6抗体说明书Anti-CYP2D6抗体资料
CYP2D6抗体说明书Anti-CYP2D6抗体资料
Cat.Number: Rs-1027R Quantitysize: 0.1ml （dilutewithpH7.4 0.01MPBSordiluentofantibody） CYP2D6抗体说明书Anti-CYP2D6抗体资料 Background:commonlyprescribeddrugs.Itssubstratesincludedebrisoquine,anadrenergic-blockingdrug;sparteineandpropafenone,bothanti-arrythmicdrugs;andamitryptiline,ananti-depressant.Thegeneishighlypolymorphicinthepopulation;certainallelesresultinthepoormetabolizerphenotype,characterizedbyadecreasedabilitytometabolizetheenzyme'ssubstrates.CytochromeP4502D6isthemoleculartargetofautoantibodiesagainstthe"liverkidneymicrosomalantigen1"（LKM1）.
CYP2D6抗体说明书Anti-CYP2D6抗体资料 Alsoknownas:CytochromeP4502D6;CPD6;CYP2D;CYP2D6;CYP2DL1;CYPIID6;CytochromeP450family2subfamilyDpolypeptide6;Debrisoquine4hydroxylase;EC1.14.14.1;Flavoproteinlinkedmonooxygenase;MGC120389;MGC120390;Microsomalmonooxygenase;P450DB1;P450C2D;P450DB1;Xenobioticmonooxygenase.CYP2D6抗体说明书Anti-CYP2D6抗体资料 Specificity: · anti-CYP2D6isarabbitmonoclonalantibodyunconjugated · specificforCYP2D6ofhuman,rat,mouseandchicken ·epitopemappingneartheCterminusofCYP2D6ofhuman,ratmouseandchicken·human,rat,mouseandchickencrossreacted · useforwesternblotting,elisa,immunoprecipitation andimmunohistochemistry· ProteinAaffinitychromatographypurification,purity:>95%·Isotype:IgG ·molwt:48kDa Application: ·Westernblotting:1:100-500·Immunohistochemistry:1:100-500·ELISA:1:500-1000· Optimalworkingdilutionsmustbedeterminedbytheenduser.CYP2D6抗体说明书Anti-CYP2D6抗体资料 Storage: Storeat–20ºCforoneyear.Avoidrepeatedfreeze/thawcycles.Thelyophilizedantibodyisstableatroomtemperatureforatleastonemonthandforgreaterthanayearwhenkeptat-20ºC.WhenreconstitutedinsterilepH7.40.01MPBSordiluentofantibodytheantibodyisstableforatleasttwoweeksat2-4ºC. ImportantNote: Thisproductassuppliedis intendedforresearchuseonly,notforuseinhuman,therapeuticordiagnosticapplications.
2004-07-13
