Anti-β-catenin/β-cats 抗体说明书

Anti-β-catenin/β-cats抗体说明书

Anti-β-catenin/β-cats抗体说明书

Cat.Number: Rs-1165R Quantitysize: 0.1ml/0.2ml (dilutewithpH7.4   0.01MPBSordiluentofantibody) Background: Beta-cateninisanadherensjunctionprotein.Adherensjunctions(AJs;alsocalledthezonulaadherens)arecriticalfortheestablishmentandmaintenanceofepitheliallayers,suchasthoseliningorgansurfaces.AJsmediateadhesionbetweencells,communicateasignalthatneioringcellsarepresent,andanchortheactincytoskeleton.Inservingtheseroles,AJsregulatenormalcellgrowthandbehavior.Atseveralstagesofembryogenesis,woundhea领,andtumorcellmetastasis,cellsformandleaveepithelia.Thisprocess,whichinvolvesthedisruptionand reestablishmentofepithelialcell-cellcontacts,mayberegulatedbythedisassemblyandassemblyofAJs.AJsmayalsofunctioninthetransmissionofthe'contact inhibition'signal,whichinstructscellstostopdividingonceanepithelialsheetiscomplete. 

Anti-β-catenin/β-cats抗体说明书

Specificity:     ·anti-β-catenin/β-catsisarabbitmonoclonalantibodyunconjugated                 ·specificforβ-catenin/β-catsofhuman,mo,rat,chicken               ·epitopemappingnearthe β-catenin/β-catsofhuman,mo,rat,chicken· useforwesternblotting,elisa,immunoprecipitation                    andimmunohistochemistry· ProteinGaffinitychromatographypurification,purity:>95%·Isotype:IgG  · molwt:92kDa Application:    ·Westernblotting:1:100-500·Immunohistochemistry:1:100-500·ELISA:1:500-1000· Optimalworkingdilutionsmustbedeterminedbytheenduser. Storage:  Storeat–20ºCforoneyear.Avoidrepeatedfreeze/thawcycles.Thelyophilizedantibodyisstableatroomtemperatureforatleastonemonthandforgreaterthanayearwhenkeptat-20ºC.WhenreconstitutedinsterilepH7.40.01MPBSordiluentofantibodytheantibodyisstableforatleasttwoweeksat2-4ºC. ImportantNote: Thisproductassuppliedis intendedforresearchuseonly,notforuseinhuman,therapeuticordiagnosticapplications.

Anti-β-catenin/β-cats抗体说明书

  
2004-07-13