RabbitAnti-XAF1抗体antibody说明书
RabbitAnti-XAF1抗体antibody说明书(XIAP-associatedfactor1)FROM:SantaCruz
CatalogNumber:Rs-1308RQuantitysize:0.1ml(dilutewithpH7.40.01MPBSorantibodydiluent)
Background:X-linkedinhibitorofapoptosis(XIAP;MIM300079)isapotentmemberoftheIAPfamily.AllmembersofthisfamilypossessbaculoviralIAP(BIR)repeats,cysteine-richdomainsofapproximately80aminoacidsthatbindandinhibitcaspases(e.g.,CASP3;MIM600636).XIAPhas3BIRdomainsandaC-terminalRINGzincfingerthatpossessesE3ubiquitinligase(seeMIM601623)activity.XAF1antagonizestheanticaspaseactivityofXIAPandmaybeimportantinmediatingapoptosisresistanceincancercells Specificity: ·anti-XAF1isaRabbitmonoclonalantibodyunconjugated·specificforXAF1ofhu,mo,rat,·epitopemappingneartheN-terminusofXAF1ofhu,mo,rat·useforwesternblotting,elisa,immunoprecipitationandimmunohistochemistry·ProteinGaffinitychromatographypurification,purity:>95%·Isotype:IgG·molwt:32kDa
Application: ·Westernblotting1:100-500·Immunohistochemistry1:100-500·ELISA1:500-1000·Optimalworkingdilutionsmustbedeterminedbytheenduser.
Storage:Storeat–20ºCforoneyear.Avoidrepeatedfreeze/thawcycles.Thelyophilizedantibodyisstableatroomtemperatureforatleastonemonthandforgreaterthanayearwhenkeptat-20ºC.WhenreconstitutedinsterilepH7.40.01MPBSordiluentofantibody,theantibodyisstableforatleasttwoweeksat2-4ºC.ImportantNote:Thisproductassuppliedisintendedforresearchuseonly,notforuseinhuman,therapeuticordiagnosticapplications. RabbitAnti-XAF1抗体antibody说明书
2004-07-13