日本IBL老年痴呆检测试剂盒及抗体简介及说明书

文档简介Amyloidplaquesarecomposedprimarilyofamyloid-beta（Aβ）peptidesderivedfromproteolyticcleavageofamyloidprecursorprotein（APP）,andareconsideredtoplayapivotalroleinAlzheimer'sdisease（AD）pathogenesis.Presently,ADisdiagnosedaftertheonsetofclinicalmanifestations.WiththearrivalofnoveltherapeuticagentsfortreatmentofAD,thereisanurgentneedforbiomarkerstodetectearlystagesofAD.MeasurementofplasmaAβhasbeensuggestedasaninexpensiveandnon-invasivetooltodiagnoseADandtomonitorAβmodifyingtherapies.However,themajorityofcross-sectionalstudiesonplasmaAβlevelsinhumanshavenotshowndifferencesbetweenindividualswithADcomparedtocontrols.Similarly,cross-sectionalstudiesofmouseplasmaAβhaveyieldedinconsistenttrendsindifferentmousemodels.However,longitudinalstudiesappeartobemorepromisinginhumans.Recently,effortstomodifyplasmaAβlevelsusingmodulatorshaveshownsomepromise.Inthisreview,wewillsummarizethepresentdataonplasmaAβinhumansandmousemodelsofAD.WewilldiscussthepotentialofmodulatorsofAβlevelsinplasmaincludingantibodiesandinsulin,andthechallengesassociatedwithmeasuringplasmaAβ.ModulatorsofplasmaAβmayprovideanimportanttooltooptimizeplasmaAβlevels,andmayimprovethediagnosticpotentialofthisapproach.Keywords老年痴呆症类试剂编号产品名称规格范围单价备注27713HumanAmyloidβ（1-40）淀粉样蛋白β（1-40）96T7.81-500pg/mL4620.00IBL27718HumanAmyloidβ（1-40）（FL）淀粉样蛋白β（1-40）（FL）96T1.56-100pg/mL4620.00IBL27720Mouse/RatAmyloidβ（1-40）HighSpecific淀粉样蛋白β（1-40）高特异性,小鼠\大鼠96T1.56-100pg/mL4620.00IBL27714HumanAmyloidβ（1-40）（N）淀粉样蛋白β（1-40）（N）96T15.63-1,000pg/mL4620.00IBL27711HumanAmyloidβ（1-42）淀粉样蛋白β（1-42）96T12.5-800pg/mL4620.00IBL27712HumanAmyloidβ（1-42）（N）淀粉样蛋白β（1-42）（N）96T6.25-400pg/mL4620.00IBL27710HumanAmyloidβ（1-43）（FL）AssayKit人淀粉样蛋白β（1-43）（FL）检测试剂盒96T2.34-150pg/ml0.51-32.5pmol/L6720.00IBL27721Mouse/RatAmyloidβ（1-42）AssayKit小鼠/大鼠淀粉样蛋白β（1-42）检测试剂盒96T1.56-100pg/ml0.35-22.6pmol/L6720.00IBL编号产品名称规格范围单价备注27729HumanAmyloidβ（1-x）淀粉样蛋白β（1-x）96T7.81-500pg/mL4620.00IBL27716HumanAmyloidβ（N3pE-42）淀粉样蛋白β（N2pE-42）96T7.75-496pg/mL4620.00IBL27717HumanAmyloidβ（1-38）（FL）淀粉样蛋白（1-38）（FL）96T9.38600pg/mL6720.00IBL27719HumanAmyloidβ（1-42）（FL）淀粉样蛋白β（1-42）（FL）96T4620.00IBL27418HumanAmyloidβ（N3PE-40）淀粉样蛋白（N3PE-40）96T3.13200pg/mL5040.00IBL27725HumanAmyloidβOligomers（82E1-specific）淀粉样蛋白寡聚体96T18.981215pmol/mL6720.00IBL27731HumansAPP,Total（highlysensitive）可溶性淀粉样前体蛋白总（超敏）96T4620.00IBL27415sAPPαmouse,rat可溶性淀粉样前体蛋白α,小鼠\大鼠96T10-640pg/mL4620.00IBL27734HumansAPPα（highlysensitive）可溶性淀粉样前体蛋白（超敏）96T4620.00IBL27733HumansAPPβ-sw（highlysensitive）可溶性淀粉样前体蛋白-sw（超敏）96T0.3925ng/mL4620.00IBL27732HumansAPPβHumansAPP可溶性淀粉样前体蛋白96T4620.00IBL27998Humansolubleα-klothoAssayKit人可溶性α-klotho蛋白检测试剂盒96T93.75-6000pg/ml6720.00IBL27752BACE1human,mouse,ratBACE1,人\小鼠\大鼠96T1.56-100ng/mL4620.00IBL27762α2,6-Sialyltransferasehuman,mouse,ratα2,6唾液酸转换酶（E41型）,人\小鼠\大鼠96T1.0970ng/mL4620.00IBL27408α2,6-Sialyltransferase（E41Form）,ratα2,6唾液酸转换酶（E41型）,大鼠96T0.31-20ng/mL4620.00IBL27776APPβCTF,human淀粉样前体蛋白β,细胞上清,人96T0.19-12pmol/L4620.00IBL27766Bisphenol（BPA）双酚A96T0.3-100ng/ml4620.00IBL27784GLP-1ActiveFormAssayKit胰高血糖素样蛋白-1活性型检测试剂盒96T1.25-80poml/L4.1-263.8pg/ml4620.00IBL27785MouseLRGAssayKit小鼠富亮氨酸α2-糖蛋白检测试剂盒96T0.25-16ng/ml6720.00IBL27758HumanNapsinAAssayKit人新天冬氨酸蛋白酶A检测试剂盒96T3.91-250ng/ml6720.00IBL