emfret公司血小板消除抗体r300说明书

文档简介#R300产品资料货号R300同种型(isotype)大鼠IgG(Wistar)含量0.5mgpurifiedimmunoglobulinsinPBS,sterilefiltered包装1ML浓度0.5mg/ml本产品只用于科研，不用于诊断，也不属于YL用品特异性:ThisantibodypreparationcontainsamixtureofpurifiedratmonoclonalantibodiesdirectedagainstmouseGPIba(CD42b).TargetingofthisreceptorwithdivalentIgGsresultsinprofoundandirreversibleFc-independentplateletdepletioninmice1,2.Plateletdepletionisfrequentlyusedtostudythegeneralroleofplateletsin(patho-)physiology3.制备:抗体是杂交瘤细胞上清通过G-Sepharose纯化所得，内毒素含量小于0.0025EU/g保存和运输：4度保存和运输，保质期为6个月，无菌保存不含防腐剂，分装保存-20度Z少可以保存一年以上，但请避免反复冻融使用方法:按动物体重注射抗体量为2g抗体/g动物体重60分钟内可以去除血小板95%以上，建议每次注射100-200L抗体（用无菌PBS稀释）。引用文献:1.BergmeierW,RackebrandtK,SchroderW,ZirngiblH,NieswandtB.(2000)StructuralandfunctionalcharacterizationofthemousevonWillebrandfactorreceptorGPIb-IXwithnovelmonoclonalantibodies.Blood.95:886-93.2.NieswandtB,BergmeierW,RackebrandtK,GessnerJE,andZirngiblH.(2000)Identificationofcriticalantigen-specificmechanismsinthedevelopmentofimmunethrombocytopenicpurpurainmice.Blood.96:2520-27.3.ElzeyBD,TianJ,JensenRJetal.(2003)Platelet-mediatedmodulationofadaptiveimmunity.Acommunicationlinkbetweeninnateandadaptiveimmunecompartments.Immunity.19:9-19.联系电话：4006551678QQ：4006551678email:fige007@163.com