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y1個人de双人舞 2018-12-08
Tetrabutylammoniumhydroxidesolution,Mobilephase,pH7.0Phosphatebuffer,Resolutionsolution,Standardpreparation,andChromatographicsystem—ProceedasdirectedintheAssayunderCefi... Tetrabutylammonium hydroxide solution,Mobile phase,pH7.0Phosphate buffer,Resolution solution,Standard preparation,and Chromatographic system— Proceed as directed in the Assayunder Cefixime. Assay preparation— Constitute Cefixime for Oral Suspension as directed in the labeling.Quantitatively dilute an accurately measured volume of the suspension thus obtained,freshly mixed and free from air bubbles,with pH7.0Phosphate bufferto obtain a solution having a concentration of about 0.2mg of cefixime per mL. Procedure— Proceed as directed in the Assayunder Cefixime.Calculate the quantity,in mg,of cefixime (C16H15N5O7S2)in each mLof the constituted suspension prepared from the Cefixime for Oral Suspension taken by the formula: (LC/D)(rU/rS),in which Lis the labeled quantity,in mg per mL,of cefixime in the constituted suspension,Dis the concentration,in mg per mL,of cefixime in the Assay preparationon the basis of the labeled quantity in the constituted suspension and the extent of dilution,and the other terms are as defined therein.
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