AN36 Determination of Oxalate in Urine by Ion Chro

INTRODUCTION
Urinary oxalate was successfully detennined by ion
chromatography with suppressed conductivity detection.
Ion chromatography using ~ IonPac@AS4A anion chro-
matographic column is a method recognized by the U.S.
Pharmacopaeia (USP) for detennining oxalate in calcium
gluconate! This method can be perfonned in less than 10
minutes. Since the analysis is perfonned at pH 9.2, the
decomposition of urinary ascorbate to oxalate is
minimized. The analysis is selective, rapid, sensitive, and
requires no sample pretreatment other than dilution. .
The measurement of oxalate in urine is important in
the diagnosis of hereditary and enteric hyperoxaluria and
in the evaluation and management of patients with urinary
~alculi ("stones"). Calculi are deposited chemicals in
compact fonn, and these concretions are frequently found
in the urinary tract. 赛默飞ICS5000多功能离子色谱