Bruker Introduces Novel Solid-State NMR Probe with

World’s Fastest 111 kHz Magic-Angle Spinning (MAS) Probe Enables Highest Performance NMR Analysis up to 1 GHz on Biological Solids and Materials with Unprecedented Convenience

Novel 111 kHz CP-MAS Probe

World’s Fastest 111 kHz Magic-Angle Spinning (MAS) Probe Enables Highest Performance NMR Analysis up to 1 GHz on Biological Solids and Materials with Unprecedented Convenience

ASILOMAR, California April 20, 2015 At the 56th Experimental Nuclear Magnetic Resonance Conference (www.enc-conference.org), Bruker (NASDAQ: BRKR) this week is introducing a unique, new ultra-high speed MAS probe together with a new MAS III controller. The new 111 kHz MAS probe, with 0.7 mm sample diameter and a sample volume of 500nl, which has been demonstrated up to 1 GHz proton frequency, delivers excellent sensitivity and the fastest spinning frequency available on the market for access to new applications in the solid-state NMR analysis of biosolids, as well as in materials science.

Solid-state NMR is a growing discipline, providing unique structural and dynamics information on various materials and biological solids in their native state, such as membrane-embedded proteins. The additional spectral resolution provided by very fast Magic Angle Spinning (MAS) allows novel detection techniques for structural and functional characterization of complex molecules. The new 111kHz CP-MAS probe will be useful for large, rigid proteins and those with paramagnetic centers in solid phase, and for the structure elucidation and improvement of advanced materials, such as battery components.

The new 111 kHz CPMAS probe extends the Bruker line-up of high speed MAS probes, comprising of 1.9 and 1.3 mm probes, now with a 0.7mm MAS system. This gives researchers great flexibility in terms of sample volume and spinning requirements, depending on the sample of interest. A new control unit, the MAS III, ensures stable regulation even at very high rotation rates. The 111 kHz MAS probe is avilable for Bruker standard-bore and wide-bore NMR magnets and comes with dedicated tools for convenient fil领 and hand领 of the small diameter rotors and caps.

"The ultra-fast magic angle spinning capabilities of Bruker’s 111 kHz MAS probe allows for the direct and high resolution observation of proton resonances from complex biomolecules,” stated Professor Lyndon Emsley from the Ecole Normale Supérieure de Lyon, France. He continued: ”We get double the resolution in protonated samples compared to 60 kHz spinning, and we were especially pleased to obtain a 1 GHz version of this break-through MAS probe, with which we have measured never-before-seen ultra-high field, ultra-fast MAS data. As such, it is a great new tool in our solid-state NMR arsenal for the structure determination of proteins, a critical need for studying disease mechanisms."

About Bruker Corporation
For more than 50 years, Bruker has enabled scientists to make breakthrough discoveries and develop new applications that improve the quality of human life. Bruker’s high-performance scientific research instruments and high-value analytical solutions enable scientists to explore life and materials at molecular, cellular and microscopic levels. In close cooperation with our customers, Bruker is enab领 innovation, productivity and customer success in life science molecular research, in applied and pharma applications, in microscopy, nano-analysis and industrial applications, as well as in cell biology, preclinical imaging, clinical research, microbiology and molecular diagnostics.

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