锘海生物科学仪器(上海)有限公司
锘海生物科学仪器(上海)有限公司

Visikol TOX 骨骼透明化试剂

使用Visikol TOX 骨骼透明化试剂DART通量improve30%!

Increase DART throughput up to 30% with Visikol TOX

Visikol TOX是一种非破坏性和快速的骨骼可视化方法, 其工作原理是使软组织透明,而不是消化它们。TOX 是一种非破坏性的,能创造出更坚固、更结实的标本, 以一种更安全、更简单、更容易使用的过程取代传统 的基于KOH的骨骼处理步骤

应用: 快速处理胎儿动物组织以检测组织病理学异常 对整个动物骨骼系统的大体形态学评估


从Alden Benjamin Dawson在1926年S次发表了KOH和Alizarin 的骨骼可视化概念以来,这个过程基本上没有改变。尽管这一 过程在90多年来一直是黄金标准,但它是一个缓慢而乏味的过 程。为了改进这一过程,我们利用ZGVisikol组织透明化技术来 创建Visikol TOX,使骨骼快速可视化而不破坏组织。


Visikol TOX 骨骼透明化试剂

·        Non-destructiveand rapid visualization

·        2-6 dayspecimen processing

·        Reducedoversight

·        Non-toxic reagents 

Background on skeletalvisualization in DART studies

Since Alden Benjamin Dawson firstpublished the concept of skeletal visualization with KOH and Alizarin in 1926,the process has largely been unchanged. CRO's and researchers utilize thisdigestive process to render biological tissues transparent so that they caneasily visualize skeletal features. While this process has been thegold-standard for over 90 years, it is a slow and tedious process that requiresconstant oversight. To improve this process, we have leveraged our proprietaryVisikol tissue clearing technology to create Visikol TOX that enables rapidskeletal visualization without tissue destruction.

Beyond Skeletal Visualization

Optical CT

With Visikol's improvements in the processing of animal skeletons forevaluation, many researchers ask us if we can also improve the evaluation ofthese specimens. Digitizing and automating skeletal evaluation with Optical CTis a an active area of research for our team.


 


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