Recombinant Human ACE2 Protein, His Tag

产品编号 KMPH1835

产品名称 Recombinant Human ACE2 Protein, His Tag

分子名称 ACE2

产品别称 Angiotensin-converting enzyme 2, ACE2

物种 Human

宿主 HEK293 Cells

应用 ELISA, WB

规格 100ug, 1mg

来源 A DNA sequence encoding the human ACE2 (NP_068576.1) (Gln18-Ser740) was expressed with a polyhistidine tag at the C-terminus.

纯度 ≥95% as determined by SDS-PAGE.

内毒素水平 < 1.0 EU per μg of the protein as determined by the LAL method.

缓冲体系 Lyophilized from sterile PBS, pH 7.4.

产品背景 Angiotensin-converting enzyme 2 (ACE2) is an enzyme attached to the cell membranes of cells located in the lungs, arteries, heart, kidney, and intestines. ACE2 lowers blood pressure by catalyzing the hydrolysis of angiotensin II into angiotensin (1–7). ACE2 counters the activity of the related angiotensin-converting enzyme (ACE) by reducing the amount of angiotensin-II and increasing Ang(1-7), making it a promising drug target for treating cardiovascular diseases. ACE2 also serves as the entry point into cells for some coronaviruses.

保存条件  Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.