RS2000系列生物学X-ray辐照仪，可以直接取代传统铯和钴源同位素辐照仪。在剂量均一性、安全性、稳定性、试验重复性等方面更为，已成为生命科学研究领域中的重要科研工具！目前，欧美各国的生物医学科研机构已较少选择同位素辐照仪，而绿色环保、剂量均匀性更佳的Rad
Source公司细胞与动物X-ray辐照仪已成为科研领域；
RS2000系列生物学X-ray辐照仪，拥有众多领xian科技：
ZG反射样品室、高安全性屏蔽技术、射线束过滤技术、杂射线滤出装置、简化易操作触控技术、业内最高的剂量均一性，剂量均一性约为±2.5%，业内**一款≥95%；
剂量率可调:0.1~16Gy/min（=10~1600rad/min
=10~1600cGy/min）；
创新ZG--Patented*
RAD+ chamber --* Patent No; 6,389,099 Rad Source uses validations from NIST to validate
their equipment. In the case of our laboratory irradiators (RS 2000) the AAPM
guide to laboratory calibration is used. In either case output from Rad Source
irradiators is calibrated to international standards insuring its performance
anywhere in the world；
RAD
SOURCE为生物学X射线辐照仪领域世界领导品牌，科研机构产品，RAD
SOURCE被认为是高精密、先进辐照技术及高质量的代表，性能稳定，拥有最大的市场份额与科研用户的好评。
RAD
SOURCE
RS2000系列产品不但成为了美国本土科研机构的，也得到了世界多国高水平科研机构的广泛认可，如：德国、法国、英国、瑞士、意大利、日本、新加坡等；在全球300多家研究机构和生物制药研发企业中运转，其性能和品质得到了全球市场的充分验证；辐照仪从2009年起正式供应ZG科研机构，已被30多家科研平台所选用，性能和品质也得到了国内用户的广泛认可。
RS2000系列生物学X-ray辐照仪，广泛应用于以下各研究领域
饲养层细胞
干细胞
骨sui移植
肿瘤学
免疫学
DNA损伤相关
信号转导
基因组学
放射生物学
小动物辐照
药物研发
等生物医学领域
Welcome
to RAD Source
Since
1997 Rad Source Technologies has been the expert in providing renewable,
non-isotope, ionizing radiation replacements for self-shielded gamma
irradiators. Currently, there are over 300 renowned hospital, university, and
pharmaceutical research institutions using Rad Source X-ray technology. To find
out more about our equipment, select your application and you will find
equipment specifications, literature references, white papers, training videos,
discussion forums, as well as other helpful info；
REASONS
WHY THE
RAD
SOURCE RS 2000 X-RAY IRRADIATOR
IS
THE SYSTEM OF CHOICE FOR YOUR
RESEARCH
AND BIOLOGICAL IRRADIATION REQUIREMENTS
The RS
2000 is a research & biological irradiator that features the following
advantages:
The RS
2000 is self-contained and requires no external coo领 system
NO
Nuclear Site license or secure/shielded room is needed
The
RS 2000 is ideal for small animal research when using our patented RAD
+ reflective cage enclosure. This unique and patented feature
provides for a dose rate within the cage of 1.2 Gy/min (120 rads/min or the same
as gamma irradiator) and the dose distribution is better than 94% across the
entire field (much better than a gamma irradiator). The RAD+ is
designed to hold one standard Allentown filtered rearing cage. (Three of which
are supplies with the system.) This feature improves animal husbandry by
allowing transport and irradiation of the animals inside a filtered environment
mitigating cross-contamination issues. Because the animals are irradiated in
their cage, multiple mice can be irradiated during one cycle. IF itis
important for you to have reproducible results that equate to theirradiation
standard of Cesium - the only choice is the RS 2000 with .3mm of Copper
filter irradiating at 160 kV AT 25 mA (NEW 225 kV available).
The
RS 2000 is ideal for targeted tumor irradiation using our spot beam collimator
or custom animal shielding and offers variable dose rates to the
target.
For Cells and
other research the RS
2000 has dose rates of >5 Gy/min (500 rads/min.) filtered and up to
>17 Gy/min unfiltered.
This
is the only system available that allows for 160 kV operation @ 25 mA (not “AND
or OR” but AT 25 mA)
“Plug
and Play” installation: Installation, dose-mapping & in-service in one
day.
Mounted
on wheels
Footprint
33” X 42” (82.8 cm X 106.7 cm) and weighs 1250 lbs (567 kg).
Simple
touch screen operators’ panel for ease of use and operation.
Please
review the information on our website: www.radsource.com
Rad
Source is the recognized expert in the field of x-ray irradiation. We
developed the only US-FDA approved blood irradiator for replacing Cs irradiators
and are the leaders in high dose, high volume irradiation systems
worldwide
The
RS 2000 首ld be the choice for your next
professional
quality biological and research irradiator
Features
· “Plug and Play” Installation
· Unit is mounted on caster wheels for easy movement
· Self-contained coo领
· Easy access to built-in calibration port
· Specialized filtration eliminates lower energy X-rays
· Optimal for split-dose delivery
· Easy to use touch screen operation
· CE Marked & Compliant
· Renewable Ionizing Radiation
· No NRC License Required
· No shielded or secure room required
· No disposal costs
部分科研机构文献
RAD SOURCE RS2000系列产品得到了广泛应用，文献发表在以下期刊：Cancer Res.、BLOOD、PANS、CELL、Stem
Cell Biology、JEM、Nature、The Journal of Immunology、Hematology
and Stem Cells、Stem Cells、PLoS Biology、Liver、I Int. J. Biol. Sci.、THE
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS、MOLECULAR
AND CELLULAR BIOLOGY、Experimental Hematology等。
1、DNA
damage checkpoint control in cells exposed to ionizing radiation
NATURE
George
Iliakis*,1, Ya Wang2, Jun Guan2 and Huichen Wang2
1Institute
of Medical Radiation Biology, University of Essen Medical School, Hufelanstrasse
55, 45122 Essen, Germany; 2Department of Radiation Oncology, Kimmel Cancer
Center, Jefferson Medical College, Philadelphia, PA 19107, USA
2、Ionizing
radiation-induced long-term expression of senescence markers in mice is
independent of p53 and immune status
CELL
Centre
de recherche CHU Ste-Justine, Montre´ al, QC, Canada； 2Lawrence Berkeley
National Laboratory, Berkeley, CA, USA
3Buck
Institute for Age Research, Novato, CA, USA；4Department of Biochemistry and
Molecular Genetics, University of Colorado Denver, School of Medicine, Aurora,
CO, USA
3、Nuclear
Localization of p38 MAPK in Response to DNA Damage
I
Int. J. Biol. Sci. 2009, 5
C.
David Wood1, Tina M. Thornton1, Guadalupe Sabio2, Roger A. Davis2,
1.
Department of Medicine/Immunobiology Program, University of Vermont,
Bur领ton, VT 05405. USA.
2.
Program in Molecular Medicine, University of Massachusetts, Worcester, MA
01605.Correspondence to: Mercedes Rincon
Received:
2009.04.30; Accepted: 2009.06.10; Published: 2009.06.16
4、Passive
and Active Mechanisms Trap Activated CD8+ T Cells in the ...
The
Journal of Immunology
Six-
to 8-wk-old mice were irradiated with 1000 rad (10 Gy) as a single dose from an
RS2000
x-ray
irradiator (Rad Source; Rad Source Technologies, Coral Springs, FL) and used as
recipients.
Mature
T cells were depleted from donor bone ...
www.jimmunol.org/cgilcontent/full/172/9/5222
5、Expression
of common chromosomal fragile site genes, VVWOX/FRA 16D ..
MOLECULAR
CARCINOGENESIS
fluency
were irradiated in RS2000 X-ray Irradiator. (Rad Source Technologies, Inc., Boca
Raton, FL).
Control cells were sham-irradiated in both the UV-. C and ionizing radiation
(IR) experiments.
For BPDE. treatment,8t-dihydroxy-9 ... doLwiley.com
6、Complete
differentiation of CD8+ T cells activated locally within ...
JEM
6
8-wk-old recipient mice were irradiated with a dose of 10 Gy (1000 rad) using an
RS2000 X-ray irradiator (RadSource Technologies). Depletion of mature T
lymphocytes from donor bone marrow
cells was achieved by incubation with anti-CD4 ...
7、An
orally bioavailable parthenolide analog selectively eradicates acute myelogenous
leukemia stem and progenitor cells
BLOOD
Monica
L. Guzman,1 Randall M. Rossi,1 Sundar Neelakantan,2 Xiaojie Li,1 Cheryl
A.
8、Ku86
Modulates DNA Topoisomerase I–Mediated Radiosensitization, but not
Cytotoxicity, in Mammalian Cells
Cancer
Res 2005
Shyh-Jen
Shih, Tara Erbele, and Allan Y. Chen
Department
of Radiation Oncology, University of California Davis Medical Center,
Sacramento,California
9、Transcellular
biosynthesis of cysteinyl leukotrienes in vivo during mouse peritoneal
Inflammation
PANS
Simona
Zarini1, Miguel A. Gijo´ n1, Aaron E. Ransome, Robert C. Murphy2
Department
of Pharmacology, University of Colorado Denver, Mail Stop 8303, 12801
East 17th
Avenue, Aurora Communicated by K. Frank Austen, Brigham and Women’s
Hospital, Boston,
MA, April 7, 2009 (received for review February 23, 2009)
10、Irradiation
Selects for p53-Deficient Hematopoietic Progenitors
PLoS
Biology
Andriy
Marusyk1,2¤, Christopher C. Porter1,3, Vadym Zaberezhnyy1
DeGregori1,2,3,4*
Department
of Biochemistry and Molecular Genetics, University of Colorado Denver School
of Medicine,
Aurora, Colorado, United States of America, 2 Program in Molecular
Biology, University
of Colorado Denver School of Medicine, Aurora, Colorado, United States of
America
11、Kupffer
cell heterogeneity: functional properties of bone marrow–derived and sessile
hepatic
macrophages
BLOOD
Ingo
Klein, 1,2 Judith C. Cornejo,3 Noelle K. Polakos,2 Beena John,2 Sherry
A.
1David
H Smith Center for Vaccine Biology and Immunology, Aab Institute for
Biomedical
Research,
University of Rochester School of Medicine and Dentistry, NY;
Received
February 11, 2007; Accepted July 25, 2007.
12、Irradiation
Alters Selection for Oncogenic Mutations in Hematopoietic
Progenitors
Cancer
Res 2009
Andriy
Marusyk,1,2 Matias Casa′s-Selves,1,2 Curtis J. Henry,1,4 Vadym
Zaberezhnyy,1
Jelena
Klawitter,5 Uwe Christians,5 and James DeGregori1,2,3,4
1Department
of Biochemistry and Molecular Genetics, 2Program in Molecular
Biology,
3Department
of Pediatrics, 4Integrated
Department of
Immunology; and 5Department of Anesthesiology, University of
Colorado
Denver
School of Medicine, Aurora, Colorado
13、Progression
of Pancreatic Adenocarcinoma Is Significantly Impeded with a Combination
of
Vaccine and COX-2 Inhibition1
The
Journal of Immunology
Pinku
Mukherjee,2* Gargi D. Basu,† Teresa L. Tinder,* Durai B.
Subramani,*
Judy
M. Bradley,* Million Arefayene,‡ Todd Skaar,‡ and Giovanni De
Petris§
长按识别二维码查看信息详情