A Water-Borne Adhesive Modeled after the Sandcastle Glue of P. californic

文档简介PolyacrylateglueproteinanalogsofthegluesecretedbyPhragmatopomacalifornica,amarineposynthesizedwithphosphate,primaryamine,andcatecholsidechainswithmolarratiossimilartothproteins.AqueousmixturesofthemimeticpolyelectrolytescondensedintoliquidcomplexcoacervneutralpH.Wetcorticalbonespecimensbondedwiththecoacervates,oxidativelycrosslinkedthrosidechains,hadbondstrengthsnearly40%ofthestrengthofacommercialcyanoacrylate.Theuniqpropertiesofcomplexcoacervatesmaybeidealfordevelopmentofclinicallyusefuladhesivesandbiomaterials.