匹伐他汀杂质列表

文档简介匹伐他汀杂质列表深圳远扬化学技术有限公司主营医药标准品及杂质对照品，以下杂质备有库存，可当天发货，价格优惠：匹伐他汀杂质，曲氟尿苷杂质，依鲁替尼杂质，奥贝胆酸杂质，依美斯汀杂质，卡格列净杂质，利格列汀杂质，西格列汀杂质，埃索美拉唑杂质，LCZ696杂质，恩杂鲁胺杂质，艾曲波帕杂质，非布司他杂质，托匹司他杂质，乐伐替尼杂质，奥拉帕尼杂质，阿维巴坦杂质，奥美拉唑杂质，普卡必利杂质，西他沙星杂质，泊沙康唑杂质，替格瑞洛杂质，托法替尼杂质，决奈达隆杂质，阿奇霉素杂质等。匹伐他汀钙背景及前程：冠心病是威胁人类健康和生命的常见病和多发病，以低密度脂蛋白(LDL)升高为特征的高胆固醇血症则是诱发冠心病的主要危险因子之一。常用的降血脂药如烟酸类、树脂类或贝特类等LX都难尽人意，降脂作用**的是被称为他汀类(statins)的药物。他汀类药物共同的作用机制是都属于3羟3甲基戊二酰辅酶A(HMGCoA)还原酶YZ剂，目前在世界广泛应用的主要有6种：洛伐他汀(lovastatin)，普伐他汀(pravastatin)，辛伐他汀(simvastatin)，西立伐他汀(cerivastatin)，氟伐他汀(fluvastatin)和阿托伐他汀(atorvastatin)。而近期由Kowa公司开发的新型他汀类药物匹他伐他汀钙，因其良好的降胆固醇作用而被称为“超级他汀类药物”(Superstatin)。匹伐他汀杂质列表（具体结构式见附件）（若列表中无您需要的杂质，欢迎详询我司，我司可提供杂质定制服务，货期短，到货快）Pitavastatin(+)-Monocalciumbis{(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3,5-dihydroxy-6-heptenoate}PitavastatinImpurity1(3R,6E)-7-[2-cyclopropyl-4-(4-flurophenyl)-3-quinolinyl]-3-hydroxy-5-oxo-6-heptenoatePitavastatinImpurity2(3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoicacidcalciumsaltPitavastatinImpurity3(4R,6S,E)-6-[2-[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]vinyl]tetrahydro-4-hydroxypyran-2-onePitavastatinImpurity47-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoicAcidPitavastatinImpurity5(3R,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoicacidcalciumsaltPitavastatinImpurity6(3S,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoicacidcalciumsaltPitavastatinImpurity7(3R,5S,6E)-7-[2-Cyclopropyl-4-phenyl-quinolin-3-yl]-3,5-dihydroxyhept-6-enoicacidcalciumsaltPitavastatinImpurity8[[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]methyl]triphenyl-phosphoniumBromidePitavastatinImpurity9(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl]-2,2-dimethyl-1,3-dioxane-6-heptenoicacidt-butylesterPitavastatinImpurity10(3R,5S,E)-7-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxy-N-(1-phenylethyl)hept-6-enamidePitavastatinImpurity11Sodium(5S,6E)-7-[2-cyclopropyl-4-(4-flurophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoatePitavastatinImpurity12Ethyl(3R,6E)-7-[2-cyclopropyl-4-(4-flurophenyl)-3-quinolinyl]-3-hydroxy-5-oxo-6-heptenoatePitavastatinImpurity13Ethyl(5S,6E)-7-[2-cyclopropyl-4-(4-flurophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoatePitavastatinImpurity14(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoicacidmethylesterPitavastatinImpurity15(3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoicacidethylesterPitavastatinImpurity16(3R,5S)-5-(6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoicacidsodiumsaltPitavastatinImpurity172-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinemethanolPitavastatinImpurity18(3R,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoicacidethylesterPitavastatinImpurity19(3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoicacidethylesterPitavastatinImpurity20(3S,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoicacidethylesterPitavastatinImpurity21(3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoicAcidtert-ButylEsterPitavastatinImpurity222-((4R,6S)-6-((E)-2-(2-Cyclopropyl-4-phenylquinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)aceticAcidtert-ButylEster