肝静脉三支汇合血流动力学的粒子成像测量

Despite rapid advancements in the patient-specific
hemodynamic analysis of systemic arterial anatomies, limited
attention has been given to the characterization of major
venous flow components, such as the hepatic venous confluence.
A detailed investigation of hepatic flow structures is
essential to better understand the origin of characteristic
abnormal venous flow patterns observed in patients with
cardiovascular venous disease. The present study incorporates
transparent rapid-prototype replicas of two pediatric
hepatic venous confluence anatomies and two-component
particle image velocimetry to investigate the primary flow
structures influencing the inferior vena cava outflow. Novel
jet flow regimes are reported at physiologically relevant mean
venous conditions. The sensitivity of fluid unsteadiness and
hydraulic resistance to multiple-inlet flow regimes is documented.
Pressure drop measurements, jet flow characterization,
and blood damage assessments are also performed.
Results indicate that the orientation of the inlets significantly
influences the major unsteady flow structures and power loss
characteristics of this complex venous flow junction. Compared
to out-of-plane arranged inlet vessel configuration, the
internal flow field observed in planar inlet configurations was
less sensitive to the venous inlet flow split. Under pathological
flow conditions, the effective pressure drop increased as
much as 77% compared to the healthy flow state. Experimental
flow field results presented here can serve as a
benchmark case for the surgical optimization of complex
anatomical confluences including visceral hemodynamics as
well as for the experimental validation of high-resolution
computational fluid dynamics solvers applied to anatomical
confluences with multiple inlets and outlets. 德国LaVision PIV/PLIF粒子成像测速场仪